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ASCO: For Chemo’s Nausea, Olanzapine Beats Metoclopramide

For patients receiving highly emetogenic chemotherapy who experience breakthrough chemotherapy-induced nausea and vomiting, treatment with olanzapine (Zyprexa) is significantly better than treatment with metoclopramide.

Remission of Schizophrenia Seen With Amisulpride, Clozapine

Overall, 45 and 44% on amisulpride and olanzapine, respectively, achieved remission (P=.87). Twenty-eight of the 40 patients not in remission started clozapine; 28% of the 18 patients who completed treatment achieved remission.

Antipsychotic Tx Linked to Adiposity Changes in Youths

The researchers found that from baseline to week 12, the dual-energy X-ray absorptiometry percentage total body fat increased by 1.18, 4.12, and 1.66% for risperidone, olanzapine, and aripiprazole, respectively, and was significantly greater for olanzapine than risperidone or aripiprazole.