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BRAF V600 Targetable in Some Nonmelanoma Cancers

For some, but not all, nonmelanoma cancers, BRAF V600 is a targetable oncogene, with activity seen in non-small-cell lung cancer and Erdheim-Chester disease and Langerhans'-cell histiocytosis.
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Bipolar Androgen Therapy May Boost Hormonal Tx in Prostate CA

A treatment strategy called bipolar androgen therapy - where patients alternate between low and high levels of testosterone - might make prostate tumors more responsive to standard hormonal therapy, according to a small study.