Among patients with available thyroid function test results, levothyroxine often initiated to treat subclinical hypothyroidism (61 percent)
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To evaluate the association, the study authors utilized healthcare databases from Ontario, Canada to identify adults 66 years of age and older with no history of AF who filled at least 1 prescription for levothyroxine.
The propensity score-matched longitudinal study aimed to compare the efficacy of generic and brand-name formulations of levothyroxine in achieving and maintaining target thyrotropin levels.
The study, which was conducted at Kaiser Permanente Colorado, aimed to compare the longitudinal stability of TSH in patients taking synthetic levothyroxine vs desiccated thyroid products.
Fresenius Kabi has announced the availability of Levothyroxine Sodium Injection Solution in 100mcg per 5mL, 200mcg per 5mL and 500mcg per 5mL single-dose vials.
Tirosint-SOL (levothyroxine sodium oral solution) has been made available by IBSA Pharma for the treatment of hypothyroidism and pituitary thyrotropin suppression.
Significantly lower total T4 absorption was noted.
The FDA have approved Tirosint-SOL, a liquid form of levothyroxine; a synthetic form of the thyroid hormone thyroxine.
Objective: The aim of this study was to determine the extent of drug interactions affecting levothyroxine, using study drugs often co-administered to patients on long-term levothyroxine therapy. Design: A retrospective population analysis linking biochemistry and prescription data between 1 January 1993 and 31 December 2012 was used.
A trend toward levothyroxine treatment of more marginal degrees of hypothyroidism and a substantial risk of developing a suppressed thyrotropin level following therapy has been observed.