Fresenius Kabi has announced the availability of Levothyroxine Sodium Injection Solution in 100mcg per 5mL, 200mcg per 5mL and 500mcg per 5mL single-dose vials.
To evaluate the association, the study authors utilized healthcare databases from Ontario, Canada to identify adults 66 years of age and older with no history of AF who filled at least 1 prescription for levothyroxine.
Significantly lower total T4 absorption was noted.
A trend toward levothyroxine treatment of more marginal degrees of hypothyroidism and a substantial risk of developing a suppressed thyrotropin level following therapy has been observed.
A recent review has found insufficient consistent data exist to recommend a change in use of levothyroxine as the only drug needed to treat hypothyroidism.
Objective: The aim of this study was to determine the extent of drug interactions affecting levothyroxine, using study drugs often co-administered to patients on long-term levothyroxine therapy. Design: A retrospective population analysis linking biochemistry and prescription data between 1 January 1993 and 31 December 2012 was used.
Soy products appear to interfere with levothyroxine absorption and can exacerbate congenital hypothyroidism in infants and young children.
Synthroid was associated with an 11% lower likelihood of having TSH labs out of range when compared with similar patients taking generic levothyroxine.
The study, which was conducted at Kaiser Permanente Colorado, aimed to compare the longitudinal stability of TSH in patients taking synthetic levothyroxine vs desiccated thyroid products.