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Novel Non-Stimulant Weight Management Aid Cleared by FDA

Gelesis announced that the Food and Drug Administration (FDA) has cleared Plenity (Gelesis100) to aid in weight management for overweight and obese adults, in conjunction with diet and exercise. Available in capsule form, Plenity, a non-systemic, superabsorbent hydrogel, is intended for use in adults with a body mass index (BMI) of 25–40kg/m2 and is taken…
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Clinical Challenge: Thickening of Nose Skin

A 51-year-old woman requests treatment for thickening of the skin of her nose. The condition has been gradually worsening over the past 2 years. She drinks alcohol in moderation and does not smoke. She takes medication for hypertension. Prior treatments for her nasal condition include doxycycline, metronidazole, and topical ivermectin, all of which were ineffectual.
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Mayzent Approved to Treat Relapsing Forms of Multiple Sclerosis

The Food and Drug Administration (FDA) has approved Mayzent (siponimod) for the treatment of relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, in adults. Siponimod, a sphingosine-1-phosphate (S1P) receptor modulator, binds with high affinity to S1P receptors 1 and 5. It blocks the capacity of…