News
Fracture Risk Up With Insulin Compared With Metformin in T2DM
Risk for major osteoporotic fractures up for insulin versus metformin for those with HbA1c <7 percent, BMI <25 kg/m2
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Coffee Does Not Impede Bioavailability of LT4 Solution
Bioavailability is equivalent for levothyroxine oral solution administered five minutes prior to coffee or under fasting conditions
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Guidelines Updated for Hospitalized Adults With Hyperglycemia
Guidelines address glycemic management in noncritically ill hospitalized adults with diabetes or newly recognized hyperglycemia
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Testosterone Therapy for Hypogonadism Not Tied to Increased CV Risk
No evidence of increase seen for short- to medium-term cardiovascular risk, but data lacking regarding long-term safety
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ADA: Once-Weekly Dulaglutide Ups Glycemic Control in Youth With T2D
Mean glycated hemoglobin level at 26 weeks increased with placebo, decreased with dulaglutide among youth with BMI >85th percentile
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Metformin Does Not Improve Survival in High-Risk Breast Cancer
Incidence rate of invasive disease-free survival events and incidence rates for death did not differ with addition of metformin, placebo
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ADA: Tirzepatide Improves Kidney Outcomes in T2DM With Increased CV Risk
Fewer renal complications seen with tirzepatide versus insulin glargine in adults with T2D and increased cardiovascular risk
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SGLT2 Inhibitors Shown to Increase Uric Acid Excretion
Increased uric acid excretion could explain, at least in part, the renoprotective effects of SGLT2 inhibitors.
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Updates Issued for Standards of Medical Care in Diabetes
Updates include effects in T2D patients of finerenone on CV outcomes in those with CKD; of SGLT2 inhibitors on heart failure, renal outcomes
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Unsweetened, Sugar-Sweetened Coffee Intake Linked to Mortality
Moderate consumption of unsweetened coffee and sugar-sweetened coffee linked to reduced risk for all-cause mortality
