Brixadi is supplied as prefilled single-dose syringes in weekly (8mg, 16mg, 24mg, 32mg) and monthly (64mg, 96mg, 128mg) doses.
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More White than Black and Hispanic patients receive buprenorphine, naloxone, benzodiazepines in 180 days after index event.
Extension through November 11, 2023, gives DEA and HHS a chance to consider revisions and public comments regarding proposals offered March 1.
Median monthly retention rate was 22.2% during January 2016 through April 2022.
Among patients experiencing precipitated withdrawal, all were discharged after symptoms resolved, with one self-directed discharge.
Patients will be required to see a doctor in person to get a first prescription for opioids, ADHD drugs
Strong recommendation made against long-term opioid therapy, especially for younger age groups, those with substance use disorder
While naloxone, a short-acting opioid antagonist, has become the standard treatment for opioid overdose, there are situations where longer-acting opioid antagonists are a more appropriate treatment choice, especially considering the rise of fentanyl. In this article, Dr Adam Bisaga, professor of psychiatry at the Columbia University Irving Medical Center in New York and research scientist at the New York State Psychiatric Institute, discusses various clinical considerations in the treatment of opioid overdose and opioid use disorder.
Proportion of overdose deaths did not increase in association with actions taken to ease access to buprenorphine
Maternal, neonatal outcomes similar to buprenorphine monotherapy