Proportion of overdose deaths did not increase in association with actions taken to ease access to buprenorphine
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Maternal, neonatal outcomes similar to buprenorphine monotherapy
More adverse dental outcomes seen with sublingual buprenorphine/naloxone compared with use of transdermal buprenorphine or oral naltrexone
The resubmitted NDA was in response to a Complete Response Letter issued by the FDA in December 2021.
Buprenorphine (as HCl) 2mg, 8mg; sublingual tabs.
Survey of 126 clinicians helps pinpoint barriers to obtaining waivers, prescribing buprenorphine
Yet, study shows buprenorphine is effective in protecting against overdose in this population
Despite increases in units per prescription, the amount of buprenorphine dispensed to Medicaid beneficiaries decreased early in the pandemic
The FDA has identified 305 cases of dental problems with buprenorphine-containing medicines dissolved in the mouth.
0.7 million of 2.4 million U.S. adults misused buprenorphine in 2019; motivations for misuse include being hooked, physical pain relief