The patients, a 71-year-old male and a 62 year-old-male, both on long-term warfarin therapy, presented to the emergency department with symptoms of COVID-19.
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Risks for diabetes complications, mortality lower with non-vitamin K antagonist oral anticoagulants versus warfarin
Apixaban the only direct oral anticoagulant linked to lower adverse event rates than warfarin for patients with atrial fibrillation across frailty levels
Risks for ischemic stroke or systemic embolism, major bleeding events lower with DOACs overall as a class versus warfarin
Tecarfarin is a novel oral vitamin K antagonist with a similar mechanism of action to warfarin, though it is metabolized differently.
Apixaban is a direct oral anticoagulant that relies less on kidney excretion.
The patient developed a generalized maculopapular rash approximately 3 hours after receiving warfarin.
Study findings revealed an increased risk of surgical intervention in women exposed to rivaroxaban.
Although more research is needed, data suggest that the cardioprotective effect of direct oral anticoagulants may extend to patients with advanced CKD.
Quality improvement effort tied to decrease in major bleeding without increase in thrombotic events