Drugs in the Pipeline
Drospirenone is a spironolactone analogue with antimineralocorticoid and antiandrogenic activity.
With regards to treatment, all of the patients responded to CSF pressure-/volume-lowering therapies (ie, acetazolamide or spironolactone).
The patient was a 32-year-old nulliparous white female who reported a 5-year history of severe hypertension, hypokalemia, and resultant systolic dysfunction.
Before stopping the drug, the patient had complete hair loss on his right temporal side, however after switching to another therapy, the hair grew back, but was white, instead of the usual black color.
Treatment with a broad-spectrum antibiotic may lead to significant changes to the gut microbiota (GM), and these changes may have lasting effects on blood pressure (BP) long after antibiotic withdrawal.