A women with a 30-year history of hypertension, hyperlipidemia and an 8-year history of systolic dysfunction is hospitalized for congestion following a 5-day river cruise.
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Before stopping the drug, the patient had complete hair loss on his right temporal side, however after switching to another therapy, the hair grew back, but was white, instead of the usual black color.
Treatment with a broad-spectrum antibiotic may lead to significant changes to the gut microbiota (GM), and these changes may have lasting effects on blood pressure (BP) long after antibiotic withdrawal.
Metronidazole-induced encephalopathy (MIE) is uncommon but usually reversible with treatment cessation. However, a case study in Neurocritical Care is the second reported death in a patient who developed severe neurotoxicity with widespread MRI abnormalities following treatment with systemic metronidazole.