ATS 2022
Is lung cancer screening using risk-based low-dose computer tomography a better predictor of lung cancer risk than age or pack/years of smoking?
Drugs in the Pipeline
The phase 3 study compared tiragolumab plus atezolizumab with placebo plus atezolizumab in adults with PD-L1 high locally advanced, unresectable or metastatic NSCLC.
Drugs in the Pipeline
The sBLA was supported by data from the phase 3 TOPAZ-1 trial.
Drugs in the Pipeline
The sBLA is supported by data from the phase 2 DESTINY-Lung01 trial, along with a phase 1 trial published in Cancer Discovery.
News
The approval was based on data demonstrating that the biosimilar product and the reference product were highly similar, and that there were no clinically meaningful differences between the agents.
Drugs in the Pipeline
Tiragolumab is a monoclonal antibody that works by binding to TIGIT, a protein receptor on immune cells, and suppresses the immune response to cancer.
Drugs in the Pipeline
Sintilimab is an investigational programmed death receptor-1 (PD-1) inhibitor.
News
The approval was based on data from the CHECKMATE-816 trial.
Clinical Charts
A comparative list of biosimilars approved by the FDA including their reference products, dosage forms and indications.
Clinical Charts
Chemotherapeutic and biologic agents for the treatment of non-small cell lung cancer (NSCLC).