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MPR Weekly Dose Podcast

MPR Weekly Dose Podcast Episode 34

This week we cover the latest COVID-19 developments including a triple antiviral therapy that looks promising, Emergency Use Authorizations granted to diagnostics and critical meds, Moderna’s investigational vaccine gets Fast Tracked, and the National Institute of Health’s remdesivir plus baricitinib trial.
Drugs in the Pipeline

Pipeline: Immunotherapies and Other Investigational Therapies for COVID-19

Updated on 6/16 While no specific treatment for coronavirus disease 2019 (COVID-19) is currently available, several therapies are being investigated globally.*    AB201 (ARCA biopharma): a selective inhibitor of tissue factor being developed as a potential treatment for COVID associated coagulopathy. Clinical testing is expected to begin in the second half of 2020. Acalabrutinib (AstraZeneca): a…
Drugs in the Pipeline

Pipeline: Investigational Antiviral Therapies for COVID-19

Updated on 6/16 While no specific treatment for coronavirus disease 2019 (COVID-19) is currently available, several therapies are being investigated globally.*    Antivirals Ampligen (AIM ImmunoTech): a broad-spectrum antiviral being developed for COVID-19 in Japan. A significant survival effect was observed in a trial evaluating mice infected with the earlier Severe Acute Respiratory Syndrome (SARS) coronavirus. …
Drugs in the Pipeline

Baricitinib Added to Topical Steroids Beneficial in Atopic Dermatitis Trial

Adding baricitinib to topical corticosteroids significantly improved disease severity in adult patients with moderate to severe atopic dermatitis, according to top-line results from BREEZE-AD7 study. The phase 3 study included 300 patients who had been diagnosed with moderate to severe atopic dermatitis for at least 12 months and had an inadequate response to topical medications.…