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Rituximab Compared With Mycophenolate Mofetil in Pemphigus Vulgaris Trial
Rituximab was found to be superior to mycophenolate mofetil (MMF) in adult patients with severe pemphigus vulgaris, according to new phase 3 trial data.
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Real-World Study Shows Mepolizumab Reduces Exacerbations in Patients With Severe Eosinophilic Asthma
Treatment with mepolizumab was associated with a significant reduction in asthma exacerbations and oral corticosteroid use in patients with severe eosinophilic asthma.
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Exploratory Data Show Additional Benefits of Vedolizumab in Ulcerative Colitis
New exploratory data published in the New England Journal of Medicine further provide evidence of the benefits of vedolizumab (Entyvio; Takeda), an integrin receptor antagonist, when compared with adalimumab (Humira; AbbVie), a tumor necrosis factor-alpha (TNFα) antagonist, in patients with moderately to severely active ulcerative colitis. In the phase 3b VARSITY study, patients were randomized…
Clinical Charts
Asthma Management: 5-11 Years of Age
Asthma management chart for children 5-11 years of age.
Clinical Charts
Asthma Management: 0-4 Years of Age
Asthma management chart for children 0-4 years of age.
Clinical Charts
Asthma Management in Youths and Adults
Asthma management in youths and adults 12 years of age and older classified by asthma severity.
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Dupilumab Safe, Effective in Pediatric Atopic Dermatitis Trial
Topline results from a phase 3 study investigating dupilumab in the treatment of pediatric patients with severe atopic dermatitis showed that the interleukin-4 receptor alpha antagonist was both safe and effective in this patient population.
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Dupixent Approved for Chronic Rhinosinusitis With Nasal Polyps
The Food and Drug Administration (FDA) has approved Dupixent (dupilumab; Sanofi and Regeneron) as an add-on maintenance treatment in adult patients with inadequately controlled chronic rhinosinusitis with nasal polyposis (CRSwNP). The approval was based on data from two phase 3 randomized, double blind, placebo controlled trials (SINUS-24 and SINUS-52) that evaluated the safety and efficacy…
Clinical Charts
Drugs Affecting Body Weight and Fat Distribution
List of therapeutic drug classes that are associated with significant weight gain and changes in fat distribution (lipodystrophy) and metabolism.
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Dupixent Approved to Treat Adolescent Patients With Moderate-to-Severe Atopic Dermatitis
The FDA has approved the use of Dupixent (dupilumab; Sanofi and Regeneron) to treat moderate-to-severe atopic dermatitis in adolescent patients 12–17 years old.
