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Severe Asthma Management

Recommendations for the management of severe asthma from the Global Initiative for Asthma (GINA).
Drugs in the Pipeline

Benralizumab Reduces OCS Use in Severe Asthma Trial

Findings from a phase 3b trial showed that a majority of patients with severe eosinophilic asthma treated with benralizumab (Fasenra; AstraZeneca), an interleukin-5 antagonist, were able to eliminate or reduce oral corticosteroid (OCS) use. The open-label, single-arm PONENTE trial assessed the efficacy and safety of reducing OCS use after initiating treatment with benralizumab in nearly…