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Durvalumab Extends Survival vs Placebo in Stage 3 Non-Small Cell Lung CA

Overall survival was significantly prolonged with durvalumab versus placebo (stratified hazard ratio [HR] for death, 0.68; P=.0025). For progression-free survival, the median duration was 17.2 months in the durvalumab group and 5.6 months in the placebo group.
ACR/ARHP 2018 Annual Meeting

Biologic DMARD Treatment Linked to Weight Gain in Inflammatory Arthritis

Small but significant increases in weight (0.02lb) and BMI (0.006 lbl P<.001 for both) were observed over time. Moreover, a negative association between DAS28 and increased weight (-0.56) as well as BMI (-0.08; P<.001 for both) was reported, implying that an increase in weight was linked to lower disease activity.
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Survival Time Compared for Brigatinib vs Crizotinib in NSCLC

The researchers found that the rate of progression-free survival was higher with brigatinib compared with crizotinib (estimated 12-month progression-free survival, 67% vs 43%; hazard ratio for disease progression or death, 0.49).