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Kidney stones correlate with an increased risk of adverse kidney outcomes, including end-stage renal disease (ESRD), Stage 3b-5 chronic kidney disease, and sustained doubling of serum creatinine, but increases in absolute rates are small.

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For patients with end-stage renal disease (ESRD), daily cocoa flavanol (CF) ingestion alleviates acute and chronic hemodialysis (HD)-induced vascular dysfunction, according to a study published online in the Clinical Journal of the American Society of Nephrology.