Drug News
Spironolactone may be an effective treatment for female pattern hair loss (FPHL), especially among patients with signs of hyperandrogenism, according to a study published in the Journal of the American Academy of Dermatology.
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For patients with heart failure with preserved ejection fraction, aldosterone blockade with spironolactone improves left ventricular diastolic function, but has no impact on maximal exercise capacity, quality of life, or patient symptoms.
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Men who had ever used spironolactone had decreased odds of prostate cancer compared with never-users, according to a study.
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For patients with resistant hypertension, adding spironolactone was significantly more effective than adding other antihypertensives, researchers presented at the European Society of Cardiology Congress 2015.
Drug News
Rate in women taking spironolactone comparable to baseline rate among healthy young women
Drug News
Spironolactone did not significantly reduce a composite outcome end point in heart failure patients with a preserved ejection fraction.
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For patients with heart failure with preserved ejection fraction (HFpEF) with an exercise-induced increase in the ratio between early mitral inflow velocity and mitral annular early diastolic velocity (E/e'), spironolactone is associated with improved exercise capacity, according to a study published in the Journal of the American College of Cardiology.
ACC.17
Among eligible patients with heart failure and reduced ejection fraction (HFrEF), use of spironolactone was associated with improved clinical outcomes.
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An antihypertensive was found to reduce side effects from corticosteroid-based creams used for certain skin diseases, reports a study published in the Journal of Investigative Dermatology.
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Spironolactone noninferior to eplerenone for preserving cardiac contractility in boys with Duchenne