News
The new packaging allows for ease of administration and convenience.
News
In an observational study, furosemide doses of 250 to 500 mg and spironolactone doses of 50 to 100 mg were independently associated with approximately 14% and 20% increased odds of hyponatremia, respectively.
News
Men who had ever used spironolactone had decreased odds of prostate cancer compared with never-users, according to a study.
News
First FDA-approved oral liquid dosage form of the potassium-sparing diuretic spironolactone.
ESC 2017
Several sub-studies investigated the superior efficacy of spironolactone in RHTN and whether there was potential benefit with amiloride in the same population.
News
CaroSpir, an aldosterone antagonist, works primarily through competitive binding of receptors at the aldosterone-dependent sodium-potassium exchange site in the distal convoluted renal tube.
ACC.17
Among eligible patients with heart failure and reduced ejection fraction (HFrEF), use of spironolactone was associated with improved clinical outcomes.
News
Despite an increasing emphasis on HFmrEF over the past several years, there is a lack of authoritative guidance surrounding therapeutic approaches for these patients.
News, Urological Disorders
A list of medications routinely prescribed in primary care practice that should be used cautiously or avoided in patients with chronic kidney disease (CKD) was compiled in a recently published study in the Annals of Pharmacotherapy.
News
Exeltis USA announced the commercial launch of Slynd (drospirenone), which is indicated for use by females of reproductive potential to prevent pregnancy. Slynd is a progestin-only contraceptive that lowers the risk of becoming pregnant primarily by suppressing ovulation. It contains the synthetic progestin drospirenone in a 4mg dosage strength that is given in a 24/4…