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Study shows that all behavioral outcomes favor e-cigarette users across the motivational spectrum for quitting.

Cytisinicline well tolerated with only 2.9% of participants discontinuing due to an adverse event.

Combination of a patch and fast-acting nicotine replacement therapy also effective.

Significant direct association seen between estrogen use, progestogen use, combined hormone therapy with gastroesophageal reflux disease.

Adjusted prevalence of nicotine dependence was lower for those aged 18 to 25, 26 to 34, 35 to 49 vs those aged 50 and older.