News
Guideline Addresses Anorectal Abscess; Anal, Rectovaginal Fistulas
Clinical guidelines updated for management of anorectal abscess, fistula-in-ano, and rectovaginal fistula
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Drugs in the Pipeline
Pfizer Testing Lyme Disease Vaccine Candidate in Phase 3 Trial
VLA15 is a 6-valent protein subunit vaccine that targets the outer surface protein A of Borrelia burgdorferi.
News
Study: Women Less Likely to Receive Appropriate CKD Care
Even women meeting objective criteria for CKD and nephrology referral were disadvantaged, according to investigators.
Drugs in the Pipeline
Xanomeline-Trospium Improves Schizophrenia Symptoms in Phase 3 Trial
The phase 3 EMERGENT-2 trial included 252 patients with schizophrenia who were experiencing symptoms of psychosis.
News
HPV Vaccination May Cut Risk for CIN2+ Recurrence
Effect estimate stronger for CIN2+ for disease related to HPV subtypes HPV 16 or HPV 18
Drugs in the Pipeline
FDA Rejects Pimavanserin sNDA for Alzheimer Disease Psychosis
The sNDA for Alzheimer disease psychosis included data from the phase 3 HARMONY and phase 2 Study-019 trials.
News
Stopping RAS Inhibitors After AKI Ups Risk for Adverse Events
Findings may aid physicians in their clinical decision-making in the absence of randomized clinical trial data, according to investigators.
Drugs in the Pipeline
Pembrolizumab Combos Miss Primary Endpoints in Liver, Prostate Cancer Trials
The LEAP-002 study evaluated pembrolizumab plus lenvatinib in patients with uHCC; the KEYNOTE-921 study evaluated pembrolizumab plus docetaxel in patients with mCRPC.
News
Evidence Updated on Myocarditis After mRNA COVID-19 Vaccination
Incidence of myocarditis probably higher after vaccination with mRNA-1273 vs BNT162b2, lower with increased interval between doses
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Stelara Approved for Pediatric Psoriatic Arthritis
The approval is supported by evidence from adequate and well-controlled studies of Stelara.
