Drugs in the Pipeline
Baricitinib Alone Authorized for COVID-19 Under Revised EUA
The update was based on data from the COV-BARRIER study.
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Drugs in the Pipeline
Early Data Show Potential Benefit of Acalabrutinib in Severe COVID-19
Acalabrutinib, a Bruton tyrosine kinase (BTK) inhibitor, appears to reduce respiratory distress as well as the hyperinflammatory immune response associated with coronavirus disease 2019.
News
INOpulse Inhaled Nitric Oxide to Be Assessed for COVID-19 in Phase 3 Study
The Food and Drug Administration has cleared the initiation of a phase 3 trial evaluating INOpulse® inhaled nitric oxide (iNO) therapy (Bellerophon Therapeutics) in patients with coronavirus disease 2019 (COVID-19).
Drugs in the Pipeline
NIH Trial Evaluating Remdesivir Plus Baricitinib for COVID-19 Initiated
Baricitinib, a JAK inhibitor, is currently approved in the US for rheumatoid arthritis.
Drugs in the Pipeline
Pipeline: Immunotherapies and Other Investigational Therapies for COVID-19
Updated on 6/16 While no specific treatment for coronavirus disease 2019 (COVID-19) is currently available, several therapies are being investigated globally.* AB201 (ARCA biopharma): a selective inhibitor of tissue factor being developed as a potential treatment for COVID associated coagulopathy. Clinical testing is expected to begin in the second half of 2020. Acalabrutinib (AstraZeneca): a…
Drugs in the Pipeline
Sarilumab COVID-19 Trial to Include Only “Critical” Patients Following Results of Phase 2 Portion
Sarilumab is currently marketed under the brand name Kevzara for the treatment of moderately to severely active rheumatoid arthritis in adults who have had an inadequate response or intolerance to 1 or more disease-modifying antirheumatic drugs.
Drugs in the Pipeline
Pipeline: Investigational Therapies for COVID-19
Currently, there are no antivirals licensed by the FDA to treat patients with COVID-19.
News
NIH Trial Evaluating Hydroxychloroquine for COVID-19 Underway
Currently, there are no approved treatments for COVID-19, however, several investigational therapies are in the works.
