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New Tablet Formulation of Calquence Approved for CLL, SLL, MCL

August 5, 2022

The approval was based on data from the phase 1 ELEVATE-PLUS trials, which showed the acalabrutinib 100mg tablets were bioequivalent to the acalabrutinib 100mg capsules.

DDW 2022, News

Concomitant PPI and Advanced Therapy Linked to Worse Outcomes in IBD

May 26, 2022

A team of investigators evaluated the effects of concomitant use of PPIs and advanced therapy on health care resources in patients with IBD.

News

Dupixent Gets FDA Approval for Eosinophilic Esophagitis

May 20, 2022

The approval was based on efficacy and safety data from a phase 3 trial, which included two 24-week treatment periods in patients 12 years of age and older with EoE.

Drugs in the Pipeline

Vonoprazan NDA Submitted for Erosive Esophagitis

March 15, 2022

The application is supported by data from the pivotal phase 3 PHALCON-EE trial which compared the efficacy and safety of vonoprazan to lansoprazole in patients with erosive esophagitis.

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ASN: PPI Use May Up Risk for AKI After Cardiac Surgery

November 16, 2021

Adults receiving proton pump inhibitors have increased risk for acute kidney injury requiring dialysis following cardiac surgery

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Statin Initiation Linked to Greater Progression of Diabetes

October 5, 2021

Each individual component of the composite outcome was significantly higher among statin users

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PPI Use May Increase Risk of Community-Acquired Pneumonia

August 27, 2021

Increased incidence of CAP was noted in stroke patients using PPIs.

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Cinacalcet Does Not Up Risk for Severe Gastrointestinal Bleeding in Hemodialysis

August 25, 2021

Study is the largest to explore this potential safety issue to date.

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New Tablet Formulation of Calquence Approved for CLL, SLL, MCL

Concomitant PPI and Advanced Therapy Linked to Worse Outcomes in IBD

Dupixent Gets FDA Approval for Eosinophilic Esophagitis

Vonoprazan NDA Submitted for Erosive Esophagitis

ASN: PPI Use May Up Risk for AKI After Cardiac Surgery

Statin Initiation Linked to Greater Progression of Diabetes

PPI Use May Increase Risk of Community-Acquired Pneumonia

Cinacalcet Does Not Up Risk for Severe Gastrointestinal Bleeding in Hemodialysis