Drugs in the Pipeline, News Tofacitinib Ext-Rel Monotherapy Effective for Moderate to Severe RA After Methotrexate Withdrawal Publish Date June 12, 2019 The ORAL Shift study enrolled 694 RA patients who were inadequate responders to methotrexate alone.
Drugs in the Pipeline Upadacitinib Gets FDA’s Priority Review for Treatment of Moderate to Severe RA Publish Date February 19, 2019 The Food and Drug Administration (FDA) has accepted for Priority Review the New Drug Application (NDA) for upadacitinib (AbbVie), an investigational oral JAK1-selective inhibitor, for the treatment of moderate to severe rheumatoid arthritis (RA).