Benralizumab is an interleukin-5 receptor alpha-directed cytolytic monoclonal antibody.
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The authors write that once severe asthma is diagnosed, clinicians should determine asthma endotype (Type2-high or Type2-low) to help choose the best therapy for the patient.
A national survey showed that only about 7% of consumers read warning labeling on over-the-counter products.
The guidelines focus on three key clinical statements.
Consistent reductions in asthma attacks and improvements in lung function across a broad population of uncontrolled asthma patients.
The patient presented to the emergency department 12 hours after choking while taking her iron supplement.
Alternative corticosteroids including beclomethasone and prednisolone should be considered, particularly for long-term use.
Compared to the control group, patients who took four or more oral corticosteroid prescriptions had 1.29 times the odds of experiencing a new adverse effect within the year.
The GOLD Report includes key recommendations for personalizing treatment in stable COPD as well as guidelines for managing exacerbations.
Currently, COPD guidelines recommend that patients with acute exacerbations be treated with systemic corticosteroids for 7-14 days, however, an updated review suggests that corticosteroid treatment of a shorter duration may be as effective as conventional longer-duration therapy.