Compared to the control group, patients who took four or more oral corticosteroid prescriptions had 1.29 times the odds of experiencing a new adverse effect within the year.
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In the asthma clinical trials, the most common adverse reactions were injection site reactions, oropharyngeal pain, and eosinophilia.
Consistent reductions in asthma attacks and improvements in lung function across a broad population of uncontrolled asthma patients.
Currently, COPD guidelines recommend that patients with acute exacerbations be treated with systemic corticosteroids for 7-14 days, however, an updated review suggests that corticosteroid treatment of a shorter duration may be as effective as conventional longer-duration therapy.
The authors write that once severe asthma is diagnosed, clinicians should determine asthma endotype (Type2-high or Type2-low) to help choose the best therapy for the patient.
EGPA (formerly known as Churg-Strauss syndrome) is a condition characterized by asthma, high levels of eosinophils (a type of white blood cell that helps fight infection), and inflammation of small- to medium-sized blood vessels.
The GOLD Report includes key recommendations for personalizing treatment in stable COPD as well as guidelines for managing exacerbations.
Alternative corticosteroids including beclomethasone and prednisolone should be considered, particularly for long-term use.
The guidelines focus on three key clinical statements.
Amneal’s triamcinolone acetonide is currently the only AP-rated generic equivalent injectable suspension available.