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Diabetic nephropathy (DN) is a long-standing complication of diabetes caused by accumulating injury to the glomerular microvasculature of the kidneys. DN is frequently asymptomatic, particularly in early stages, but can be detected using annual kidney-function and albuminuria tests.

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Clinical efficacy of the oral Janus kinase inhibitor tofacitinib at Month 6 was greater than placebo and “appeared similar regardless of methotrexate dose” in patients with rheumatoid arthritis a post-hoc analysis presented at the 2015 ACR/ARHP Annual Meeting has found.