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Study: Xarelto Lowers Hospital Admissions, Costs for DVT Patients

Patients treated with Xarelto (rivaroxaban; Janssen) for deep vein thrombosis (DVT) had less frequent hospital admissions than those treated with standard low molecular weight heparin (LMWH) and warfarin, according to study data presented at the Hospital Medicine 2015 Congress.
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First-of-Kind Implant to Reduce Stroke in High-Risk Patients Approved

Boston Scientific announced that the Food and Drug Administration (FDA) has approved WATCHMAN Left Atrial Appendage Closure Device to reduce the risk of stroke in high-risk patients with non-valvular atrial fibrillation who are looking for an alternative to long-term warfarin therapy.
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Study Examines PPI Benefit in Warfarin-Related GI Bleeding

Co-treatment with proton-pump inhibitors (PPIs) in patients initiating warfarin was associated with reduced reduced risk of warfarin-related upper gastrointestinal (GI) bleeding, a study published in Gastroenterology reported.
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Drug Interaction Possible When HCV Regimens Added to Warfarin

A retrospective cohort study in the Annals of Pharmacotherapy found a clinically significant decrease in warfarin dose-response with concurrent hepatitis C treatments, especially with ombitasvir/paritaprevir/ritonavir and dasabuvir (OBV-PTV/r-DSV).
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Longer Anticoagulation May Lower Risk of Recurrent DVT, Bleeding in PE

In patients with a first episode of pulmonary embolism who took six months of anticoagulants, another 18 months of treatment with warfarin reduced the risk of blood clots and major bleeding, though the benefit was not maintained after discontinuing anticoagulation therapy, a study has shown.