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Elacestrant showed a statistically significant and clinically meaningful progression-free survival improvement compared with standard of care.

Camizestrant improved progression-free survival vs fulvestrant in postmenopausal patients with ER+, HER2- advanced breast cancer.

Statins are the most widely prescribed agents in the world. While muscle-related adverse effects associated with statins are well known, accurately quantifying their incidence to guide clinicians with respect to lipid management can be difficult, said Richard H. Karas, MD, PhD, Tufts Medical Center, Boston, at ACC.11, the American College of Cardiology’s 60th Annual Scientific Session.

Monitoring bESR1mut enabled optimization of the endocrine therapy used with a CDK4/6 inhibitor.

The duration of prior treatment with a CDK4/6 inhibitor appears to impact progression-free survival with elacestrant in ER+/HER2- metastatic breast cancer.

Multiple inflammatory markers should simultaneously be tested to best detect unresolved inflammation in pain patients according to results presented at PAINWeek 2013 from a study conducted by pain specialist Forest Tennant, MD, DrPH.

End-stage lung disease may significantly increase the risk for gastroesophageal reflux disease (GERD) in patients undergoing lung transplant without primary esophageal disease.

Clinical efficacy of the oral Janus kinase inhibitor tofacitinib at Month 6 was greater than placebo and “appeared similar regardless of methotrexate dose” in patients with rheumatoid arthritis a post-hoc analysis presented at the 2015 ACR/ARHP Annual Meeting has found.

Sarilumab administered every 2 weeks is associated with similar improvements in physical function in adult patients with rheumatoid arthritis, compared with adalimumab.

Long-term etanercept is associated with modestly better treatment retention rates than adalimumab among patients with rheumatoid arthritis (RA), according to an analysis of data from the RHUMADATA® clinical registry and database presented at the 2015 ACR/ARHP Annual Meeting.