The approval was based on data from the LIGHTHOUSE and SPOTLIGHT clinical trials.
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Greater improvements seen for blood pressure, blood sugar levels, and weight control versus DASH diet.
The increasing number of indications for second-generation antiandrogens may result in a large group of men at risk for toxic effects.
Strong recommendations made for use of polyethylene glycol, sodium picosulfate, linaclotide, plecanatide, and prucalopride.