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In seven of 22 cases, approval used new interpretations of original evidence and did not require new evidence

In 11 comparisons, antidepressants were efficacious, but they were inefficacious or evidence was inconclusive for 31 comparisons

Evidence insufficient to evaluate the benefits and harms of screening for eating disorders in adolescents and adults

Limited evidence suggests that continuing biological DMARDs may lower risk for disease flares without increasing risk for postop complications

Evidence insufficient to support a recommendation for or against screening adults, teens for eating disorders

And in second recommendation statement, evidence insufficient for screening asymptomatic older adults for impaired visual acuity

Evidence is insufficient for assessing balance of benefits and harms of OSA screening in general population

A sizable gender gap evident for risk of depression and anxiety

Evidence insufficient for assessing benefits and harms of screening for children and adolescents

Class I study shows single doses of aducanumab safe, well tolerated; class II studies show reduced amyloid deposition on brain PET at one year