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Proton Pump Inhibitor Use May Up Death Risk

The authors found that compared to the use of H2RA therapy, patients initiated on PPI therapy had a 25% increased risk of death (hazard ratio [HR] 1.25, 95% CI: 1.23-1.28).
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Does PPI Use Increase the Risk of Gynecomastia?

According to the results of a retrospective cohort study, male patients who utilize proton pump inhibitors (PPIs) appear to be at increased risk of developing gynecomastia.
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Gastric Acid Suppressant Use in the US Examined Over a 7-Year Period

To identify trends in gastric acid suppressant use, researchers analyzed data from the National Ambulatory Medical Care Survey. They classified any outpatient visit with a documented prescription for a proton pump inhibitor or histamine-2 receptor antagonist as a gastric acid suppressant use.