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Your search for non small cell lung cancer returned 23 results

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Drugs in the Pipeline

Opdivo Granted Priority Review for Advanced Renal Cancer

The FDA has accepted for filing and granted priority review to the supplemental Biologics License Application (sBLA) for Opdivo (nivolumab; BMS) for the treatment of patients with advanced renal cell carcinoma (RCC) who have received prior anti-angiogenic therapy.
Drugs in the Pipeline

Positive Phase 3 Results for Opdivo in Renal Cell Carcinoma

Bristol-Myers Squibb announced positive results from CheckMate -025, a Phase 3 study comparing Opdivo (nivolumab) to everolimus in advanced renal cell carcinoma (RCC) after prior anti-angiogenic treatment.
Drugs in the Pipeline

FDA Designates Avelumab Orphan Drug for Skin Cancer

The FDA has granted Orphan Drug designation to the investigational cancer immunotherapy avelumab (Pfizer/Merck) for the treatment of Merkel cell carcinoma (MCC).
News

Survival Benefit Compared With Immune Checkpoint Inhibitors in NSCLC

Pembrolizumab plus chemotherapy demonstrated the greatest survival benefit compared with other immune checkpoint inhibitors (ICIs) across all PD-L1 expression levels in the first-line treatment of advanced non-small cell lung cancer (NSCLC), according to a meta-analysis presented at the IASLC 2019 World Conference on Lung Cancer. Randomized clinical trials evaluating first-line ICI alone or in combination…
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Selpercatinib Promising in RET Fusion-Positive NSCLC

Treatment with selpercatinib (LOXO-292) was associated with high objective response rate (ORR) in heavily pretreated patients with RET fusion-positive non-small cell lung cancer (NSCLC), according to research presented at the IASLC 2019 World Conference on Lung Cancer. Researchers from Memorial Sloan Kettering Cancer Center presented data from the LIBRETTO-001 (LOXO-292 Investigated to Block RETaltered Tumors)…
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Durvalumab Plus Chemotherapy Improves Overall Survival in Extensive-Stage SCLC

Durvalumab added to standard-of-care (SoC) chemotherapy demonstrated significantly improved overall survival (OS) in treatment-naive patients with extensive-stage small cell lung cancer (SCLC), according to a phase 3 study presented at the IASLC 2019 World Conference on Lung Cancer. The CASPIAN trial was a randomized, open-label, multicenter, global, phase 3 study evaluating durvalumab in combination with…
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Do BMI, Age Affect Clinical Response to Immune Checkpoint Inhibitors in Patients With NSCLC?

Obesity and age do not appear to influence the survival of patients with non-small cell lung cancer (NSCLC) treated with programmed death receptor-1 (PD-1)/programmed cell death ligand 1 (PD-L1) immune checkpoint inhibitors (ICI), according to an analysis presented at the IASLC 2019 World Conference on Lung Cancer. To better understand how age and body mass…
Drugs in the Pipeline

FDA to Review Ready-to-Dilute Pemetrexed Formulation

The FDA has accepted for review the New Drug Application (NDA) for Eagle's ready-to-dilute (RTD) Pemetrexed Injection 25mg/mL for the treatment of locally advanced or metastatic nonsquamous non-small cell lung cancer and mesothelioma (in combination with cisplatin).