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To investigate an appropriate dosing strategy for 4F-PCC (Kcentra; CSL Behring) in obese patients, the authors conducted a retrospective analysis comparing the reversal of warfarin using adjusted (N=28) vs actual body weight (N=50).
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To compare the incidence of hospitalization for upper GI tract bleeding, researchers used US Medicare beneficiary files to identify a cohort of patients that were ≥30 years old who initiated oral anticoagulation therapy with apixaban, dabigatran, rivaroxaban, or warfarin, with or without PPI cotherapy.
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For this review, researchers performed an extensive literature search for studies and cases where an adverse drug reaction occurred likely due to an interaction between an herbal and a prescribed medicine.
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The Food and Drug Administration (FDA) has approved updated labeling for several hepatitis C virus (HCV) infection treatments.
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The ROCKET-AF study provided the primary data to support the 2011 approval of Xarelto.
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Patients may not be fully aware of the foods and drugs that can interfere with warfarin treatment and cause serious side effects
