News
The ready-to-dilute formulation was developed to eliminate the reconstitution step with Alimta.
News
Krazati is a highly selective and potent oral small molecule inhibitor of KRASG12C.
News
The approval was based on data from a phase 3 POSEIDON study.
News
Findings showed that treatment with cemiplimab-rwlc plus platinum-based chemotherapy demonstrated a statistically significant improvement in overall survival.
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Alymsys is a vascular endothelial growth factor inhibitor.
Drugs in the Pipeline
Sapanisertib is a dual mTORC 1/2 inhibitor that targets a key survival mechanism in KEAP1/NRF2-mutated tumor cells.
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Vegzelma is a vascular endothelial growth factor inhibitor.
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The approvals were based on data from the LIBRETTO-001 trial.
News
The accelerated approval was based on data from the phase 2 DESTINY-Lung02 trial that included adults with HER2-mutant metastatic NSCLC after 1 prior systemic therapy.
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The full approval was based on data from an additional 63 adults with metastatic NSCLC with confirmed MET exon 14 skipping as well as 22 months of follow-up time.