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Metronidazole-induced encephalopathy (MIE) is uncommon but usually reversible with treatment cessation. However, a case study in Neurocritical Care is the second reported death in a patient who developed severe neurotoxicity with widespread MRI abnormalities following treatment with systemic metronidazole.

An adolescent presented with persistent upper-extremity pain, redness, and 
axillary swelling upon lifting weights.