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Clear management guidelines are needed for AKI during immune checkpoint inhibitor therapy, according to investigators.

A team of investigators evaluated the effects of concomitant use of PPIs and advanced therapy on health care resources in patients with IBD.

The application is supported by data from the pivotal phase 3 PHALCON-EE trial which compared the efficacy and safety of vonoprazan to lansoprazole in patients with erosive esophagitis.

Increased incidence of CAP was noted in stroke patients using PPIs.

Study is the largest to explore this potential safety issue to date.

The most common inappropriate medications included proton pump inhibitors, alpha blockers, and NSAIDs.

Avoiding inappropriate use and overdosing of drugs with nephrotoxic effects is an important strategy to prevent hospital-acquired AKI in children, according to investigators.

Prompt diagnosis of AKI and the ability to rule out immune checkpoint inhibitors as the cause may allow patients to continue with cancer immunotherapy.