ZOLOFT
Generic Name for ZOLOFT
Sertraline (as HCl) 25mg, 50mg, 100mg; scored tabs.
Legal Classification:
Rx
Pharmacological Class for ZOLOFT
SSRI.
Manufacturer of ZOLOFT
Pfizer Labs
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Indications for ZOLOFT
Depression. Premenstrual dysphoric disorder (PMDD).
Adult dose for ZOLOFT
Give once daily (AM or PM). Depression: initially 50mg/day, may increase at 1-week intervals; max 200mg/day. PMDD: give either for entire menstrual cycle or only during luteal phase. Luteal phase dosing: initially 50mg/day; if no response, may increase to 100mg/day, starting each cycle at 50mg/day for 3 days. Entire cycle dosing: initially 50mg/day, if no response, may increase by 50mg/cycle to max 150mg/day.
Children's dosing for ZOLOFT
Not recommended.
Also:
Contraindications for ZOLOFT
During or within 14 days of MAOIs. Concomitant pimozide. Oral soln: concomitant disulfiram.
Warnings/Precautions for ZOLOFT
Monitor for mania/hypomania. Seizure disorders. Suicidal tendencies. Hepatic dysfunction (reduce dose or prolong dosing interval). Cardiac disease. Conditions that affect metabolism or hemodynamic response. Volume depleted. Reevaluate periodically in long-term use. Write ℞ for smallest practical amount. Elderly. Labor & delivery. Pregnancy (Cat.C). Nursing mothers.
Interactions for ZOLOFT
See Contraindications. Avoid alcohol. May potentiate or be potentiated by cimetidine, protein bound drugs (eg, warfarin, digitoxin). Caution with other CNS drugs and drugs metabolized by CYP2D6 (eg, tricyclics, flecainide, propafenone). Potentiates diazepam, tolbutamide. Monitor lithium, warfarin, tricyclics. Monitor patients on sumatriptan for serotonin syndrome (eg, weakness, incoordination, hyperreflexia).
Adverse Reactions for ZOLOFT
GI upset, insomnia, somnolence, sexual dysfunction, tremor, dry mouth, sweating, anorexia, weight loss, anxiety, decreased libido, hyponatremia, weak uricosuric effect.
How is ZOLOFT supplied?
Tabs 25mg—50
50mg, 100mg—100, 500
Conc—60mL (w. dropper)
Related Disease:
Depression
Premenstrual dysphoric disorder