ZAROXOLYN

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Generic Name for ZAROXOLYN

Metolazone 2.5mg, 5mg, 10mg; tabs.

Legal Classification:

Rx

Pharmacological Class for ZAROXOLYN

Diuretic (quinazoline).

Manufacturer of ZAROXOLYN

UCB Inc.

Indications for ZAROXOLYN

Hypertension.

Adult dose for ZAROXOLYN

2.5–5mg once daily.

Children's dosing for ZAROXOLYN

Not recommended.

Contraindications for ZAROXOLYN

Do not interchange brands. Anuria. Hepatic coma or precoma. Sulfonamide allergy.

Warnings/Precautions for ZAROXOLYN

For switching with Mykrox see literature. Renal or hepatic dysfunction. Azotemia. Arrhythmias. Diabetes. Gout. SLE. Monitor fluids, electrolytes, BUN. K+ supplements or K+-sparing diuretics may be needed. Discontinue if electrolyte disorders develop rapidly. Pregnancy (Cat.B). Nursing mothers: not recommended.

Interactions for ZAROXOLYN

Digitalis, lithium toxicity. Furosemide, other diuretics increase fluid loss. Antagonizes antidiabetic, antigout medications, methenamine. Monitor anticoagulants. May potentiate nondepolarizing muscle relaxants, tubocurarine. ACTH, corticosteroids increase hypokalemia risk. Antagonized by NSAIDs, salicylates. Orthostatic hypotension, enhanced antihypertensive effects with alcohol, CNS depressants, other antihypertensives.

Adverse Reactions for ZAROXOLYN

Electrolyte/metabolic disturbances (esp. hypokalemia), syncope, hyperglycemia, hyperuricemia, hypercalcemia, orthostatic hypotension, photosensitivity, GI disturbances, blood dyscrasias, chest or joint pain, cutaneous vasculitis.

How is ZAROXOLYN supplied?

Tabs—100, 1000

Related Disease:

Hypertension

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