ADD THIS DRUG TO MY LIST

Select the drug indication to add to your list

ZAROXOLYN
Edema
Hypertension
Compare To Related Drugs
View/Edit/Compare Drugs In My List

Only 4 drugs may be compared at once

REMOVE SELECTED | COMPARE SELECTED

Drug Name:

ZAROXOLYN Rx

Generic Name and Formulations:
Metolazone 2.5mg, 5mg, 10mg; tabs.

Company:
UCB Inc.

e-Prescribe this drug via Surescripts


Therapeutic Use:

Product Resources »
  • Product Information
  • Coupons, Samples & Vouchers
  • Patient Education and Assistance

Indications for ZAROXOLYN:

Edema.

Adult Dose for ZAROXOLYN:

5–20mg once daily.

Children's Dose for ZAROXOLYN:

Not recommended.

Pharmacological Class:

Quinazoline.

Contraindications:

Do not interchange brands. Anuria. Hepatic coma or precoma. Sulfonamide allergy.

Warnings/Precautions:

For switching with Mykrox see literature. Renal or hepatic dysfunction. Azotemia. Arrhythmias. Diabetes. Gout. SLE. Monitor fluids, electrolytes, BUN. K+ supplements or K+-sparing diuretics may be needed. Discontinue if electrolyte disorders develop rapidly. Pregnancy (Cat.B). Nursing mothers: not recommended.

Interactions:

Digitalis, lithium toxicity. Furosemide, other diuretics increase fluid loss. Antagonizes antidiabetic, antigout medications, methenamine. Monitor anticoagulants. May potentiate nondepolarizing muscle relaxants, tubocurarine. ACTH, corticosteroids increase hypokalemia risk. Antagonized by NSAIDs, salicylates. Orthostatic hypotension, enhanced antihypertensive effects with alcohol, CNS depressants, other antihypertensives.

Adverse Reactions:

Electrolyte/metabolic disturbances (esp. hypokalemia), syncope, hyperglycemia, hyperuricemia, hypercalcemia, orthostatic hypotension, photosensitivity, GI disturbances, blood dyscrasias, chest or joint pain, cutaneous vasculitis.

How Supplied:

Tabs—100, 1000

Indications for ZAROXOLYN:

Hypertension.

Adult Dose for ZAROXOLYN:

2.5–5mg once daily.

Children's Dose for ZAROXOLYN:

Not recommended.

Pharmacological Class:

Diuretic (quinazoline).

Contraindications:

Do not interchange brands. Anuria. Hepatic coma or precoma. Sulfonamide allergy.

Warnings/Precautions:

For switching with Mykrox see literature. Renal or hepatic dysfunction. Azotemia. Arrhythmias. Diabetes. Gout. SLE. Monitor fluids, electrolytes, BUN. K+ supplements or K+-sparing diuretics may be needed. Discontinue if electrolyte disorders develop rapidly. Pregnancy (Cat.B). Nursing mothers: not recommended.

Interactions:

Digitalis, lithium toxicity. Furosemide, other diuretics increase fluid loss. Antagonizes antidiabetic, antigout medications, methenamine. Monitor anticoagulants. May potentiate nondepolarizing muscle relaxants, tubocurarine. ACTH, corticosteroids increase hypokalemia risk. Antagonized by NSAIDs, salicylates. Orthostatic hypotension, enhanced antihypertensive effects with alcohol, CNS depressants, other antihypertensives.

Adverse Reactions:

Electrolyte/metabolic disturbances (esp. hypokalemia), syncope, hyperglycemia, hyperuricemia, hypercalcemia, orthostatic hypotension, photosensitivity, GI disturbances, blood dyscrasias, chest or joint pain, cutaneous vasculitis.

How Supplied:

Tabs—100, 1000