Generic Name and Formulations:
Ethosuximide 250mg; caps.
Company:
Pfizer Inc.
Absence seizures.
Initially: 500mg daily. Increase every 4–7 days by 250mg daily according to response; max 1.5g daily in divided doses.
<3yrs: not recommended. 3–6yrs: initially 250mg daily. >6yrs: initially 500mg daily. Increase both every 4–7 days by 250mg daily according to response; max 1.5g daily in divided doses. Usual maintenance: 20mg/kg/day in divided doses.
Succinimide.
Impaired hepatic or renal function. Change dose gradually. May precipitate tonic-clonic seizures. Monitor skin, blood, urine and liver tests. Pregnancy (Cat.D). Nursing mothers: not recommended.
Monitor phenytoin, phenobarbital, valproic acid, others.
Blood dyscrasias, drowsiness, ataxia, dizziness, hepatic, renal, behavioral, psychological and GI disorders, SLE, Stevens-Johnson syndrome (discontinue if occurs), headache, rash, gingival hyperplasia.
Hepatic.
Renal.
Caps, syrup (YES)
Caps—100; Syrup—pt