Select the drug indication to add to your list


Melanoma and other skin cancers
Only 4 drugs may be compared at once

Generic Name and Formulations:

Ipilimumab 5mg/mL; soln for IV infusion; preservative-free.

Select therapeutic use:

Indications for YERVOY:

Treatment of unresectable or ­metastatic melanoma in patients ≥12yrs. Adjuvant treatment of cutaneous melanoma in patients with pathologic involvement of regional lymph nodes >1mm who have undergone complete resection, including total lymphadenectomy.


Give by IV infusion over 90 mins. Unresectable, metastatic: 3mg/kg every 3 weeks for a maximum of 4 doses; may delay doses if toxicity occurs, but all treatment must be given within 16 weeks of the first dose. Adjuvant: 10mg/kg every 3 weeks for 4 doses, followed by 10mg/kg every 12 weeks for up to 3 years; may omit doses if toxicity occurs. Dose modifications: see full labeling.


Not established.


Severe and fatal immune-mediated adverse reactions can develop. Permanently discontinue therapy and initiate systemic high-dose corticosteroids for severe, persistent, or recurring immune-mediated reactions. Withhold dose for moderate immune-mediated adverse reactions until return to baseline, improvement to mild severity, or complete resolution, and patient is receiving <7.5mg prednisone or equivalent per day. Monitor for enterocolitis, hepatitis, dermatitis, neuropathy, endocrinopathy, and others including ocular manifestations; perform clinical chemistries including LFTs, ACTH levels, and thyroid tests at baseline and before each dose. Moderate or severe hepatic impairment. Embryo-fetal toxicity. Females of reproductive potential should use effective contraception during and for 3 months after final dose. Pregnancy. Nursing mothers: not recommended (during and for 3 months after final dose).

Pharmacological Class:

Cytotoxic T-lymphocyte antigen 4 (CTLA-4)-blocking antibody.

Adverse Reactions:

Fatigue, diarrhea, pruritus, rash, colitis, headache, weight loss, nausea, pyrexia, decreased appetite, vomiting, insomnia; immune-mediated reactions.


To enroll pregnant patients in the Pregnancy Safety Surveillance Study, call (844) 593-7869.

Generic Availability:


How Supplied:

Single-use vial (50mg, 200mg)—1

YERVOY 50mg/10ml vials (Qty:1)

appx. price $6945.00