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Skin infections (topicals)
Only 4 drugs may be compared at once

Generic Name and Formulations:

Acyclovir 5% + hydrocortisone 1%; crm.

Select therapeutic use:

Indications for XERESE:

Early treatment of recurrent herpes labialis (cold sores), to reduce likelihood of ulcerative cold sores and shorten lesion healing time in adults and adolescents (≥12yrs old).


Start as soon as possible after the first signs/symptoms emerge (ie, during the prodrome or when lesions appear). Wash and dry area. Apply topically to affected area on lips or around the mouth 5 times daily for 5 days. Avoid unnecessary rubbing of affected area to avoid aggravating or transferring infection. Do not occlude. Wash hands before and after application; wait at least 30 minutes before bathing, showering, or swimming.


Not recommended.


Immunocompromised. Reevaluate if symptoms persist more than 2 weeks. Avoid eyes, inside the mouth or nose, or on the genitals. Pregnancy (Cat. B). Nursing mothers.


Do not apply other products (makeup, sunscreen, lip balm, etc) to area during treatment.

Pharmacological Class:

Antiviral + antiinflammatory.

Adverse Reactions:

Drying, flaking, burning/tingling sensation, erythema, pigmentation changes.

How Supplied:

Crm—2g, 5g

XERESE 5g of 5%/1% tube of creams (Qty:1)

appx. price $1263.00