Viral Infections

CDC: Elevated Flu Activity Expected to Continue for Several More Weeks

By February 16, 2018

So far this season, influenza A(H3N2) viruses have predominated, but other influenza viruses are also circulating.

How Can the U.S. Improve Its Ability to Stop a New Flu Pandemic?

February 16, 2018

As an expert in public health law, I can state two things with confidence. First, the U.S. has made enormous strides in preparing for and treating the flu. And second, we still are not nearly as prepared as we need to be for the next pandemic.

Influenza vaccine not associated with increased risk of epilepsy in children

February 15, 2018

No increased risk of incident epilepsy was seen among children who received influenza vaccination during the 2009-2010 influenza season in Norway.

New Tool May Help Combat the Spread of Flu, Say Researchers

By February 09, 2018

The study was designed to test if far-UVC light could efficiently kill aerosolized influenza virus in the air.

Unexpected Toxicities Identified With Concomitant HIV, Tuberculosis Tx Use

By February 09, 2018

The study had to be cut short when 2 of 4 subjects developed serious toxicities following the third isoniazid-rifapentine dose.

FDA Approves Biktarvy to Treat HIV-1 Infection in Adults

By February 08, 2018

Biktarvy combines bictegravir, an integrase strand transfer inhibitor (INSTI), and emtricitabine (FTC) and tenofovir alafenamide (TAF), two nucleoside reverse transcriptase inhibitors (NRTIs).

Mogamulizumab Evaluated in Patients With HTLV-1-Associated Myelopathy

February 08, 2018

Findings in patients with HTLV-1-associated myelopathy-tropical spastic paraparesis

Three-Drug Combo Symfi Lo Approved for the Treatment of HIV

By February 07, 2018

Symfi Lo combines efavirenz (EFV), a non-nucleoside reverse transcriptase inhibitor (NNRTI), and lamivudine (3TC) and tenofovir disoproxil fumarate (TDF), both nucleo(t)side reverse transcriptase inhibitors.

Treatment for Smallpox Gets FDA Priority Review

By February 07, 2018

The treatment was developed under the FDA's 'Animal Rule'; where efficacy is determined in animal studies and human studies determine safety and appropriate dosing. The FDA have stated a target action date for TPOXX of August 8, 2018.

Norovirus Outbreak Hits Olympics in PyeongChang

By February 07, 2018

Around 1,200 security workers at the winter Olympics in PyeongChang are being kept in their rooms due to a norovirus outbreak that has already sickened 41 people.

Conspiracy Beliefs and Anti-Vaccination Attitudes: What's the Link?

By February 07, 2018

Incidences of measles, mumps and pertussis have increased in the U.S. for the first time in a century (WHO, 2017). To identify the 'attitude roots' of vaccine rejection, a survey was issued online and completed by 5,323 usable participants in 24 different countries.

ACIP: 2018 Recommended Immunization Schedule for Adults Released

By February 06, 2018

Changes in the 2018 adult immunization schedule from the previous year's schedule include new ACIP recommendations for the use of recombinant zoster vaccine (RZV) for adults aged 50 years or older and the use of an additional dose of measles, mumps, and rubella vaccine (MMR) in a mumps outbreak setting.

ACIP: 2018 Immunization Schedule for Children, Adolescents Available

By February 06, 2018

The recommended childhood and adolescent immunization schedules for 2018 have been approved by the American Academy of Pediatrics, the Advisory Committee on Immunization Practices of the Centers for Disease Control and Prevention (CDC), the American Academy of Family Physicians, and the American College of Obstetricians and Gynecologists.

New Formulation of HyperRAB Approved for Rabies Post-Exposure Prophylaxis

By February 06, 2018

Reduced volume of medication offers potential for fewer injections.

Patient Portal Messages, IVR Calls May Improve Flu Vaccination Rates

By February 05, 2018

Results found that among portal users, 14% (702/5,000) of portal and IVR call recipients received EHR-documented influenza vaccines.

Super Bowl Revelers May Be at Increased Risk of Being Tackled by the Flu

By February 02, 2018

Influenza related deaths have been show to increase significantly in the home counties of Super Bowl participating teams compared to non-competing counties.

Edurant Dosing Recommendations Updated for Pregnant HIV Patients

By February 02, 2018

Lower exposures of rilpivirine were observed during pregnancy, therefore viral load should be monitored closely.

Zika-Related Flaviviruses May Also Have Potential to Cause Congenital Infection

February 01, 2018

Efficient replication was reported for West Nile virus and Powassan virus in second-trimester human maternal (decidua) and fetal (chorionic villi and fetal membrane) explants, while less efficient replication was seen for CHIKV and MAYV.

Prezcobix Labeling Updated With New Drug Interactions

By January 31, 2018

Prezcobix, a combination of an HIV-1 protease inhibitor and a CYP3A inhibitor, is indicated to treat HIV-1 infection in adults.

Glecaprevir-Pibrentasvir Effective for Patients With HCV Genotype 1, 3

January 31, 2018

The researchers found that the rate of sustained virologic response at 12 weeks was 99.1% among genotype 1-infected patients in the eight-week group and 99.7% in the 12-week group.

Viral respiratory infections associated with increased risk of acute myocardial infarction

January 30, 2018

In a self-controlled case series, patients were observed to have increased incidence of hospital admissions for acute myocardial infarction (MI) within seven-days of respiratory virus detection.

Zika Vaccine Candidate Gets Fast Track Designation

By January 29, 2018

A total of 240 individuals between the ages 18 and 49 are enrolled in the Phase 1 trial of TAK-426.

CDC: Increase in Birth Defects May be Zika-Related

January 29, 2018

The researchers identified a non-statistically significant increase in total birth defects potentially related to Zika virus infection in areas with local transmission, from 2.8 to 3.0 cases per 1,000 live births in the first and second halves of 2016, respectively (P=0.10).

Neurodevelopmental Differences Examined in HIV+, HIV-Exposed Children

January 26, 2018

The researchers found that HIV+ and HEU children had lower cognitive and motor scores than their HUU peers within the meta-analysis.

CDC Examines HIV Testing Rates, Reasons For Having Never Been Tested

January 26, 2018

Overall, 38.8% of women and 53.8% of men had never been tested in 2011 to 2015.

HCV Drug May Potentially Be an Effective Treatment for Zika

By January 25, 2018

Sofosbuvir protected and rescued neural cells infected by the Zika virus in cell cultures and mouse models, and blocked transmission of the virus to mouse fetuses.

Shorter duration of glecaprevir-pibrentasvir effective against hepatitis C virus: The ENDURANCE trials

January 25, 2018

Both 8 and 12-week regimens of glecaprevir-pibrentasvir were highly efficacious in producing sustained virologic response in patients infected with hepatitis C virus (HCV) genotypes 1 and 3, and the 8-week treatment duration was noninferior to 12-week duration.

Respiratory Infections, Especially Flu, Linked to Increased MI Risk

January 25, 2018

The incidence ratio was 6.05 for admission for acute myocardial infarction during the risk interval versus the control interval. After day 7 there was no increased incidence.

HIV Privacy Breach Lawsuit Reaches Settlement

By January 24, 2018

The privacy breach occurred in July 2017, when letters outlining that beneficiaries could now pick up their medications in person were sent in envelopes with large address windows which made private health information visible.

Juluca Labeling Updated to Correct Dosing Separation Information

By January 22, 2018

Juluca was approved as a complete regimen for the treatment of HIV-1 infection in adults to replace the current antiretroviral regimen in those who are virologically suppressed on a stable antiretroviral regimen for at least 6 months with no history of treatment failure and no known substitutions associated with resistance to the individual components of Juluca.