Viral Infections

Oral HPV Infection More Common Among U.S. Men Than Women

October 17, 2017

Overall prevalence 11.5 percent in men, 3.2 percent in women; high-risk HPV also more prevalent in men

Two Vaccines to Prevent Ebola Virus Show Promise in Trial

October 13, 2017

ChAd3-EBO-Z, rVSVG-ZEBOV-GP vaccines elicit response that is maintained through 12 months

Is Post-HSIL Tx Adjuvant HPV Vaccination in HIV-Infected MSM Cost-Effective?

October 11, 2017

Adjuvant HPV vaccination could reduce anal cancer risk in HIV-infected men who have sex with men

Early-Life Antibiotic Use and Celiac Disease: Is There an Association?

October 10, 2017

The researchers found that exposure to and frequency of use of any antibiotic assessed in the study in early life or before seroconversion was not associated with the risk of developing islet or celiac disease autoimmunity.

Live Flu Vaccine Withdrawal Not Linked to Change in Immunization Rates

October 06, 2017

Withdrawal of live attenuated influenza vaccine recommendation not linked to change in rates

Most U.S. Measles Cases Linked to Unvaccinated Patients

October 04, 2017

Failure to vaccinate, rather than vaccine performance, appears to be driving transmission

Updated HCV Guidance Focuses on Additional Patient Populations

By October 03, 2017

The updates include a primer on HCV resistance and guidance on treating patients who have undergone kidney transplantation.

Elevated Coffee Intake Cuts Mortality Risk in Patients Co-Infected with HIV/HCV

October 02, 2017

Those who drink at least 3 cups daily have 50 percent lower all-cause mortality

Merck Discontinues Clinical Program for Two HCV Treatments

By September 29, 2017

The MK-3682B trial evaluated a triple-combination therapy.

Does Mandating HCV Screening Among Baby Boomers Improve Outcomes?

By September 28, 2017

Nearly three-quarters of all HCV infections in the U.S. and HCV-associated deaths occur in individuals born between 1945-1965.

Genvoya Approved for Use in Children with HIV Weighing at Least 25kg

By September 27, 2017

Based on this new data, Genvoya is now indicated to treat adult and pediatric patients weighing ≥25kg compared to the previous ≥35kg requirement.

CDC: Sexually Transmitted Diseases Hit 'Record High' in U.S.

By September 26, 2017

The majority of syphilis infections are seen particularly in gay, bisexual, and other men who have sex with men (MSM), of which half are also diagnosed with HIV.

Updated Dosing, Drug Interactions Added to Epivir Labeling

By September 26, 2017

Epivir, a nucleoside analogue (reverse transcriptase inhibitor), is currently approved to treat HIV-1 infection,

AAP Explores Major Infectious Disease Risk Factors in Team Sports

September 25, 2017

The researchers found that skin-to-skin contact with athletes who have active skin infections, environmental exposures, and physical trauma are major risk factors for infection, as well as sharing of equipment and contact with contaminated fomites.

NDA for First Darunavir-Based Single-Tab HIV Regimen Submitted

By September 25, 2017

The treatment will become the first darunavir-based, single-tablet HIV treatment, if approved.

Rapivab Approved for Use in Children with Acute Uncomplicated Influenza

By September 21, 2017

Rapivab inhibits influenza virus neuraminidase, an enzyme that releases viral particles from the plasma membrane of infected cells. The antiviral activity of peramivir was determined in cell culture.

HPV Vaccination May Protect Fertility for Some Women

By September 20, 2017

The data indicated little association between vaccination in females (FR 0.98, 95% CI: 0.90, 1.08) or males (FR 1.07, 95% CI: 0.79, 1.46) and fecundability.

AAP Publish First Guidance on Tattooing, Piercing for Adolescents

By September 18, 2017

These can occur from contamination of the inks or diluents used for tattooing.

Treating HCV Infection May Prevent Development of Chronic Kidney Disease

By September 18, 2017

Using several databases, the researchers examined the association of HCV infection with the incidence of CKD.

Experts Concerned About Study that Links Flu Vaccine to Spontaneous Abortion

By September 14, 2017

Overall, the study points to an association between spontaneous abortion and influenza vaccination receipt in the past 28 days. This link, however, proved significant only among those vaccinated in the previous season with the pH1N1-containing vaccine.

Quadrivalent Flu Vaccine Approved for Use in 5-Year-Olds

By September 14, 2017

Data from a randomized, observer-blinded, comparator-controlled study (n=2,278) evaluating children aged 5-17 years showed that Afluria Quadrivalent vaccine was non-inferior to a comparator vaccine containing the same recommended virus strains.

Researchers Identify Monocytes Crucial to Coagulation in HIV

September 11, 2017

The anticoagulant Ixolaris blocked functional activity of tissue factor in vitro and in vivo

Drop in HPV Rates in Unvaccinated Woman Shows Benefit of Herd Immunity

September 08, 2017

A significant decrease over time was seen among unvaccinated women aged 18 to 26 years, from 19.5% in 2009-2010 to 9.7% in 2013-2014.

Accuracy of Influenza Diagnostic Tests Compared

September 08, 2017

The researchers found that the pooled sensitivities for detecting influenza A using Bayesian bivariate random-effects models were 54.4% for RIDTs, 80% for DIAs, and 91.6% for NAATs.

Could a Third Vaccine Dose Aid Waning Immunity During Mumps Outbreaks?

September 08, 2017

They found that before the outbreak, 98.1% of the students had received at least 2 doses of MMR vaccine.

Additional Support Needed to Maintain PrEP Adherence in Adolescents

September 06, 2017

Per 100 person-years, the HIV seroconversion rate was 6.4. At weeks 4, 8, 12, 24, 36, and 48, tenofovir diphosphate levels consistent with a high degree of anti-HIV protection were found in 54, 47, 49, 28, 17, and 22% of participants, respectively.

Could a Change in Boarding Practices Cut the Spread of Infection on Planes?

By September 01, 2017

"It turns out that procedures that are generally good at getting people onto a plane very fast are also very bad at preventing infection," said Associate Professor of Computer Science Ashok Srinivasan.

Epstein-Barr Virus May Increase Risk for Multiple Sclerosis

August 31, 2017

The researchers found that those with MS in all three racial groups were more likely to show signs of infection with EBV.

Adverse Birth Outcomes Examined by Antiretroviral Tx Regimens

By August 25, 2017

The study authors reported that of the 11,932 infants exposed to HIV, 5780 (48.4%) of them were considered ART exposed from conception.

Insurer Breaches Client Privacy via Clear Envelope

By August 25, 2017

According to a statement from the Legal Action Center the letter was sent to individuals in Arizona, California, Georgia, Illinois, New Jersey, New York, Ohio, Pennsylvania, and Washington, D.C.