Viral Infections

Active Choice Intervention Tied to Increase in Flu Shot Rates

September 19, 2018

Compared with control practices over time, the active choice intervention correlated with a significant 9.5% increase in vaccination rates, in adjusted analyses. Similar increases were seen in vaccination rates across times of the day.

Patrons of 'Vampire Facial' Spa May Have Been Exposed to HIV

September 17, 2018

In a vampire facial - popularized by Kim Kardashian and other celebrities - a patient's blood is drawn and then injected back into the face using micro-needles.

Chest Radiograph Effective for Excluding Pediatric Pneumonia

September 12, 2018

The researchers found that 72.8% of children had negative CXRs, with 8.9% of these children clinically diagnosed with pneumonia and 9.3% given antibiotics for other bacterial syndromes.

Influenza Caused Emirates Flight to Be Briefly Quarantined at JFK

September 11, 2018

New York City health officials say passengers had influenza or other common cold viruses

Southwest Passengers May Have Been Exposed to Measles

September 10, 2018

Officials say a passenger on 4 flights was later diagnosed with measles

AAP Issues Updated Influenza Vaccine Recommendations

By September 06, 2018

According to the Centers for Disease Control and Prevention (CDC), the 2017-2018 flu season was one of the most severe - excluding pandemics - on record.

Gaps in Prevention, Management of Tickborne Diseases Identified

September 06, 2018

Diagnostic and surveillance limitations and lack of treatment options, vaccines hamper efforts

Baloxavir Superior to Placebo for Alleviating Flu Symptoms

September 06, 2018

The time to symptom alleviation was similar for baloxavir and oseltamivir. Greater reductions in viral load were seen with baloxavir vs placebo or oseltamivir 1 day after initiation of the regimen.

CDC: HPV Vaccination Rates Increasing Among Adolescents

September 05, 2018

The researchers found that coverage increased for 1 or more dose of HPV vaccine (60.4 to 65.5%), 1 or more dose of meningococcal conjugate vaccine (MenACWY; 82.2 to 85.1%), and 2 or more doses of MenACWY (39.1 to 44.3%) from 2016 to 2017.

FDA Approves Two New Oral Treatments for HIV-1 Infection

By August 31, 2018

Delstrigo is approved as a complete regimen whereas Pifeltro is to be administered in combination with other antiretrovirals.

CDC: Updated Influenza Vaccination Recommendations for 2018-2019

By August 23, 2018

In general, routine annual vaccination is recommended for all patients ≥6 months of age who have no contraindications.

1997 to 2015 Saw Increase in HIV Viral Suppression Rates

August 23, 2018

Lower odds of having detectable viral load for older adults and those using ISTI-based regimen

Catch-Up HPV Doses Effective to Age 21 Against Cervical Neoplasia

August 22, 2018

The strongest protection against CIN2+ was among women who had received at least 3 vaccine doses and had received their first dose at age 14 to 17 years (RR, 0.52) or age 18 to 20 years (RR, 0.65). In women 21 years or older at the time of first dose.

US Measles Outbreak Hits 107 Cases in 21 States, D.C.

August 20, 2018

This outbreak is on track to exceed last year's 118 reported cases in 15 states and the District of Columbia.

Ibalizumab Active in Multidrug Resistant HIV-1 Infection

August 16, 2018

The researchers found that 83% of the 40 patients in the intention-to-treat population had a decrease in viral load of at least 0.5 log10 copies per milliliter from baseline, with a mean viral-load decrease of 1.1 log10 copies per milliliter.

Long-Acting 2-Drug Injectable Noninferior to Oral 3-Drug Combo in HIV Study

By August 16, 2018

The ATLAS study enrolled 570 patients infected with HIV-1; participants were randomized to either the experimental or active comparator arms.

Integration of Opioid, Infectious Disease Treatment Needed

August 15, 2018

"All health care providers have a role in combating the OUD epidemic and its infectious disease consequences. Those who treat infectious complications of OUD are well-suited to screen for OUD and begin treatment with effective US Food and Drug Administration-approved medications," the authors write.

Labeling for Several HIV Meds Updated to Include Interaction Data With DOACs

By August 14, 2018

If Tybost is given with atazanavir or darunavir, coadministration with rivaroxaban is not recommended due to a potentially increased bleeding risk.

<i>C. difficile</i> Tied to Increased Graft Loss in Solid Organ Recipients

August 13, 2018

"These data support the importance of restrictive antibiotic use in the prevention of CDI and underscores the need for close surveillance of graft function in SOT recipients developing CDI," the authors write.

Cytovene-IV Labeling Updated to Include Additional Fertility Impairment Data

By August 10, 2018

Cytovene-IV is a deoxynucleoside analogue cytomegalovirus (CMV) DNA polymerase inhibitor.

Mavyret Labeling Updated With Dosing for Liver, Kidney Transplant Patients

By August 10, 2018

The Dosage and Administration section has been revised to state that Mavyret is recommended for 12 weeks in liver or kidney transplant recipients.

New Tick Species Spreading in the United States

August 09, 2018

The ticks can reproduce rapidly and suck so much blood from a young animal that it dies, The Times reported.

Good Outcomes for HCV-Negative Recipients of HCV Kidneys

August 07, 2018

"In summary, this trial provides reassuring (albeit preliminary) evidence that kidneys from HCV-infected donors may be safely transplanted into HCV-negative recipients," the authors write.

Rifampin Similar to Isoniazid for Preventing Active Tuberculosis

August 03, 2018

The rifampin regimen was not superior to the isoniazid regimen, as the upper boundaries of the 95% confidence interval for the rate differences of the confirmed cases and for the confirmed or clinically diagnosed cases of tuberculosis were less than the prespecified non-inferiority margin of 0.75 percentage points in cumulative incidence.

Protease Inhibitors May Worsen Outcomes in Patients With HIV + Heart Failure

August 02, 2018

The researchers found that patients who were receiving a PI had higher rates of hyperlipidemia, diabetes mellitus, and coronary artery disease.

Evidence Exists for Persistence, Transmission of Ebola Virus

August 02, 2018

"These findings underscore the need for focused prevention efforts among survivors and sustained capacity to rapidly detect and respond to new Ebola virus disease cases to prevent recurrence of a widespread outbreak," the authors write.

Canada Updates Guidelines for Hepatitis C Virus Infection

July 27, 2018

The Canadian Association for the Study of the Liver recommends birth cohort screening for individuals born from 1945 to 1975; a pretreatment evaluation of infected patients that includes clinical evaluation, viral load, genotype, and a fibrosis stage assessment.

Could Zika Virus Be a Potential Treatment for Neuroblastoma?

By July 26, 2018

Even with intensive therapy, survival among neuroblastoma patients is poor, indicating a need for alternative treatments.

WHO Targets for Chronic Hepatitis B Will Be Cost-Effective

July 26, 2018

The authors note that in order to reach the targets by 2030, approximately 14.5 million adults in at-risk populations would need to be screened to diagnose an estimated 870,000 undiagnosed cases.

WHO: Congo Ebola Outbreak Over

July 26, 2018

The last known Ebola case in Congo was in early June, but the WHO had to wait 42 days before declaring the outbreak officially over.