Generic Name and Formulations:
Liraglutide [rDNA origin] 6mg/mL; soln for SC inj.
Indications for VICTOZA:
As adjunct to diet and exercise, to improve glycemic control in type 2 diabetes.
Limitations Of use:
Not recommended as first-line treatment for patients inadequately controlled on diet and exercise. Not a substitute for insulin. Not for treating type 1 diabetes or ketoacidosis. Not studied in combination with prandial insulin or with a history of pancreatitis.
Give by SC inj in abdomen, thigh, or upper arm once daily. Initially 0.6mg/day for 1 week, then 1.2mg/day; may increase to 1.8mg/day. If >3 days elapsed since last dose, reinitiate at 0.6mg/day, then titrate. Renal impairment: caution with initiating or escalating doses.
<18yrs: not recommended.
Glucagon-like peptide-1 [GLP-1] receptor agonist.
History (personal or family) of medullary thyroid carcinoma. Multiple endocrine neoplasia syndrome type 2.
Risk of thyroid C-cell tumors; inform patients of potential risk and symptoms. Discontinue if pancreatitis is suspected; do not restart if confirmed. History of pancreatitis: consider other antidiabetic therapies. Do not reuse or share pens or needles between patients. Renal or hepatic impairment. Gastroparesis. Pregnancy (Cat.C). Nursing mothers: not recommended.
Concomitant insulin (insufficient data); administer as separate injections not adjacent to each other. Hypoglycemia with sulfonylureas or insulin (consider reducing their doses). May affect absorption of other drugs (delayed gastric emptying). Monitor digoxin.
Headache, nausea, diarrhea, antibody formation, immunogenicity reactions (eg, urticaria), constipation; rare: pancreatitis (discontinue if occurs), papillary thyroid carcinoma, anaphylactic reactions and angioedema (discontinue if occurs).
Multi-dose, pre-filled pen (3mL)—2, 3
- 3 pens of 18mg/3ml cartons (Qty:1)
- appx. price $662.00
- Paleo Diet: Should It Stay in the Stone Age?
- Risks and Recommendations: The Use of NSAIDs in Patients With Cardiovascular Disease
- Neurological Complications Caused by "Skinny Jeans"
- What's the Secret to Longevity? Lessons from "Blue Zones" Worldwide
- Peanut Allergy Drug Designated Breakthrough Therapy