Select therapeutic use:
Indications for VICOPROFEN:
Short-term (generally <10 days) management of acute pain.
≥16yrs: 1 tab every 4–6 hours as needed; max 5 tabs/day.
<16yrs: not recommended.
Aspirin allergy. 3rd trimester pregnancy. Coronary artery bypass graft surgery.
Advanced renal disease: not recommended. Head injury. Increased intracranial pressure. Acute abdomen. Active peptic ulcer. History of upper GI disease. Impaired renal, hepatic, thyroid, pulmonary, or adrenocortical function. GI or GU obstruction. Asthma. Edema. Hypertension. Heart failure. Bleeding disorders. Diabetes. Monitor blood, hepatic, renal, and visual function. Dehydration. Post-op (may suppress cough reflex). Drug abusers. Discontinue if visual or liver dysfunction occurs. Elderly. Debilitated. Pregnancy (Cat.C). Labor & delivery, nursing mothers: not recommended.
Avoid aspirin. Alcohol, other CNS depressants potentiated. May potentiate, or be potentiated by, MAOIs or tricyclic antidepressants. Increases serum lithium levels. May increase bleeding with anticoagulants. Paralytic ileus may occur with anticholinergics. May increase toxicity of methotrexate. May reduce efficacy of, and increase risk of renal failure with, ACE inhibitors, diuretics.
Opioid + NSAID.
Headache, somnolence, constipation, dizziness, GI upset/bleed, rash (discontinue if occurs), respiratory depression, anemia, mood changes, confusion, anaphylaxis; aseptic meningitis (rare); others. See literature re: risk of cardiovascular events.