VIAGRA Rx

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VIAGRA

Erectile dysfunction
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Generic Name and Formulations:

Sildenafil citrate 25mg, 50mg, 100mg; tabs.

Company:

Pfizer Inc.

Select therapeutic use:

Indications for VIAGRA:

Erectile dysfunction.

Adult:

Take 1 dose as needed about 1hr (½–4hrs) before sexual activity at frequency of up to once daily. Initially 50mg. May reduce dose to 25mg or increase to max of 100mg. Elderly, hepatic impairment, severe renal impairment, or concomitant strong CYP3A4 inhibitors: consider initial dose of 25mg. Concomitant ritonavir: max single sildenafil dose of 25mg in 48hrs. Concomitant α-blockers (patients should be stable on α-blocker therapy before starting): initially 25mg.

Children:

Not established.

Contraindications:

Concomitant organic nitrates or nitric oxide donors (eg, sodium nitroprusside). Concomitant guanylate cyclase (GC) stimulators (eg, riociguat).

Warnings/Precautions:

Confirm diagnosis. Cardiovascular disease (eg, MI, stroke, or life-threatening arrhythmia within 6 months; BP<90/50 or >170/110; unstable angina, LV outflow obstruction, impaired autonomic regulation of BP). Anatomical penile deformation. Predisposition to priapism. Underlying non-arteritic anterior ischemic optic neuropathy risk factors. Advise patients to discontinue if sudden vision or hearing loss occurs. Retinitis pigmentosa. Patients for whom sexual activity is inadvisable or contraindicated. Bleeding disorders. Active peptic ulcer. Pregnancy (Cat.B).

Interactions:

See Contraindications. Hypotension with nitrates, GC stimulators. Additive hypotensive effects with concomitant α-blockers (eg, doxazosin), antihypertensives (eg, amlodipine). Potentiated by CYP3A4 (eg, ketoconazole, itraconazole, erythromycin, saquinavir, ritonavir) or CYP2C9 inhibitors, or cimetidine. Antagonized by CYP3A4 inducers (eg, rifampin). Concomitant other erectile dysfunction treatments: not recommended.

Pharmacological Class:

Phosphodiesterase type 5 inhibitor (cGMP-specific).

Adverse Reactions:

Headache, flushing, dyspepsia, nasal congestion, back pain, myalgia, nausea, dizziness, rash, visual disturbances (eg, color tinge to vision, increased light sensitivity, blurred vision), sudden vision or hearing loss; rare: cardiovascular events, prolonged erection, priapism.

Generic Availability:

YES

How Supplied:

Tabs 25mg—30; 50mg, 100mg—1, 30, 100

VIAGRA 100mg tablets (Qty:1)

appx. price $56.00