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VIAGRA
Erectile dysfunction
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Drug Name:

VIAGRA Rx

Generic Name and Formulations:
Sildenafil citrate 25mg, 50mg, 100mg; tabs.

Company:
Pfizer Inc.



Therapeutic Use:

RECENT UPDATES

08/20/14
Updated Adults dosing regarding concomitant a-blockers.

Indications for VIAGRA:

Erectile dysfunction.

Adult Dose for VIAGRA:

Take 1 dose as needed about 1 hr (½–4 hrs) before sexual activity at frequency of up to once daily. Initially 50mg. May reduce dose to 25mg or increase to max of 100mg. Elderly, hepatic impairment, severe renal impairment, or concomitant potent CYP3A4 inhibitors (eg, erythromycin, ketoconazole, itraconazole, saquinavir): consider initial dose of 25mg. Concomitant ritonavir: max single sildenafil dose of 25mg in 48hrs. Concomitant α-blockers (patients should be stable on α-blocker therapy before starting): initially 25mg.

Children's Dose for VIAGRA:

Not established.

Pharmacological Class:

Phosphodiesterase type 5 inhibitor (cGMP-specific).

Contraindications:

Concomitant organic nitrates or nitric oxide donors (eg, sodium nitroprusside).

Warnings/Precautions:

Confirm diagnosis. Cardiovascular disease (eg, MI, stroke, or life-threatening arrhythmia within 6 months; BP<90/50 or >170/110; unstable angina, LV outflow obstruction, impaired autonomic regulation of BP). Anatomical penile deformation. Predisposition to priapism. Underlying non-arteritic anterior ischemic optic neuropathy risk factors. Advise patients to discontinue if sudden vision or hearing loss occurs. Retinitis pigmentosa. Patients for whom sexual activity is inadvisable or contraindicated. Bleeding disorders. Active peptic ulcer. Pregnancy (Cat.B).

Interactions:

Hypotension with nitrates: see Contraindications. Concomitant α-blockers (eg, doxazosin) may lead to symptomatic hypotension. Additive effects with concomitant antihypertensives (eg, amlodipine). Plasma levels increased by inhibitors of CYP3A4 (eg, ketoconazole, itraconazole, erythromycin, saquinavir, ritonavir) or CYP2C9, or cimetidine. Plasma levels reduced by inducers of CYP3A4 (eg, rifampin). Concomitant other erectile dysfunction treatments: not recommended.

Adverse Reactions:

Headache, flushing, dyspepsia, nasal congestion, back pain, myalgia, nausea, dizziness, rash, visual disturbances (eg, color tinge to vision, increased light sensitivity, blurred vision), sudden vision or hearing loss; rarely: cardiovascular events, prolonged erection, priapism.

How Supplied:

Tabs 25mg—30; 50mg, 100mg—30, 100

VIAGRA

  • 100mg tablets (Qty:10)
  • appx. price $343.00
GoodRx

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