VERELAN Rx

Indications for VERELAN:

Hypertension.

Adult Dose for VERELAN:

Take as a single dose in the AM. May sprinkle contents on applesauce; do not crush or chew contents. Over 18 yrs: usually 240mg daily; adjust in 120mg increments. Elderly, small people, others with increased sensitivity: 120mg daily; if needed, may increase daily dose to 180mg, then 240mg, then higher in 120mg increments; max 480mg daily.

Children's Dose for VERELAN:

<18yrs: not recommended.

See Also:

VERELAN PM

Pharmacological Class:

Calcium channel blocker (diphenylalkylamine).

Contraindications:

Severe left ventricular (LV) dysfunction or LV dysfunction treated with β-blockers. Moderate to severe heart failure. Hypotension. Cardiogenic shock. Sick sinus syndrome, 2^nd- or 3^rd-degree AV block, unless paced. Atrial flutter or fibrillation and an accessory bypass tract.

Warnings/Precautions:

Control mild heart failure (eg, with digitalis, diuretics). AV conduction or neuromuscular transmission disorders. Hepatic or renal dysfunction. Monitor liver function. Hypertrophic cardiomyopathy. Pregnancy (Cat.C). Nursing mothers: not recommended.

Interactions:

Potentiates alcohol, α- and β-blockers, other antihypertensives, digitalis, theophylline, neuromuscular blockers, flecainide, carbamazepine, cyclosporine. Potentiated by grapefruit juice. Avoid disopyramide; quinidine in cardiomyopathy. Potentiated by CYP3A4 inhibitors (eg, erythromycin, ritonavir); antagonized by CYP3A4 inducers (eg, rifampin). Inhalation anesthetics may potentiate cardiac depression. May increase bleeding with aspirin. Monitor theophylline, lithium, cyclosporine.

Adverse Reactions:

Hypotension, edema, AV block, bradycardia, CHF, constipation, headache, dizziness, fatigue, dyspepsia, elevated hepatic enzymes, paralytic ileus.

How Supplied:

Caps—100