Select therapeutic use:
Indications for UROXATRAL:
Benign prostatic hyperplasia (BPH). Limitations of use: not for use in children or for the treatment of hypertension.
Swallow whole. Take immediately after same meal each day. 10mg once daily.
Concomitant potent CYP3A4 inhibitors (eg, ketoconazole, itraconazole, ritonavir). Moderate or severe hepatic insufficiency.
Not for use in women. Discontinue if angina develops or worsens. Severe renal insufficiency (CrCl <30mL/min). Hypotension. Mild hepatic impairment. History of QT interval prolongation. Exclude prostate cancer prior to initiation. Cataract surgery (intraoperative floppy iris syndrome possible). Pregnancy (Cat.B).
See Contraindications. Do not use with other α-blockers. Increased hypotension with concomitant nitrates, PDE5 inhibitors, other antihypertensives. Potentiates and is potentiated by cimetidine. Potentiates cardiovascular effects of atenolol. Caution with drugs that prolong QT interval.
Dizziness, upper respiratory tract infection, headache, fatigue; postural hypotension, syncope; rare: priapism.